Bioreactor for production of products with immobilized biofilm

Details Bioreactor for production of products with immobilized biofilm Bioreactor for production of products with immobilized biofilm

1993-09-01

1995-04-04

Naff, David M.

Chemistry: molecular biology and microbiology

Miscellaneous

435174, 435176, 435177, 43524023, 435310, 435316, 435288, C12M 110, C12M 1100, C12M 500, C12M 102

Patent

active

054037425

ABSTRACT:
A bioreactor is provided for production of products by biosynthesis or biotransformation using a biofilm of immobilized cells. The bioreactor includes a horizontal cylindrical housing and a central rotatable shaft which extends along the axis of the housing. Connected to the central shaft are one or more screens which are oriented parallel to the shaft, with a small gap between the shaft and the screen. The bioreactor further includes a slidable blade which is mounted onto the shaft, through a set of poles, and which is located at a fixed distance from the screen so that the blade is made to pass over the screen by the force of gravity as the shaft rotates, as by the action of a rotating external magnet. An example of use of the bioreactor is the production of .UPSILON.-decalactone from castor oil using Tyromyces sambuceus.

REFERENCES:
patent: 3402103 (1968-09-01), Amberg et al.
patent: 3925165 (1975-12-01), Muller
patent: 4760028 (1988-07-01), deBrayne et al.
patent: 5266476 (1993-11-01), Sussman et al.

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