Bioreactor compositions with enhanced cell binding

Details Bioreactor compositions with enhanced cell binding Bioreactor compositions with enhanced cell binding

1994-08-03

1997-10-07

Davenport, Avis M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 15, 514 16, 514 17, 514 18, 514 19, 424484, 530326, 530327, 530328, 530329, 530330, 530331, 530345, A61K 3800, A61K 3802, A61K 914, C07K 500

Patent

active

056748485

ABSTRACT:
Compositions of the invention include packing materials having compounds thereon with enhanced cell binding with respect to collagen. These packing materials are useful for in vitro uses such as for cell culture in bioreactors. Suitable compounds with enhanced cell binding include synthetic peptides that mimic the conformation necessary for recognition and docking of collagen binding species (such as cell surface receptors for collagen and fibronectin) and have the amino acid residues -Ile-Ala- folded in a .beta.-bend.

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