Bioprosthetic valve

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Heart valve – Having rigid or semirigid pivoting occluder

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623 66, A61F 224

Patent

active

050806700

ABSTRACT:
A bioprosthetic valve made from a biological tissue containing collagen which has been cross-linked with a polyepoxy compound is disclosed. The valve has excellent biocompatibility and is durable and is free from calcification.

REFERENCES:
patent: 4402697 (1983-09-01), Pollock et al.
patent: 4655773 (1987-04-01), Grassi
patent: 4692164 (1987-09-01), Dzemeshkevich et al.
patent: 4792139 (1988-03-01), Nashef
Liotta, D. et al., "Low Profile Bioprosthesis for Cardiac Valve Replacement: Early Clinical Results", Cardiovascular Diseases, Bulletin of the Texas Heart Institute, vol. 4, No. 4, pp. 371-382, 1978.
Thubrikar, M. J. et al., "Role of Mechanical Stress in Calcification of Aortic Bioprosthetic Valves", in J. Thorac Cardiovasc Surg. 86:115-125, 1983.
Ferrans, V. J. et al., "Calcific Deposits in Porcine Bioprostheses Structure and Pathogenesis", Amer. J. Cardiol. 46:721-734, 1980.
Dunn, J. M. et al., "Mechanisms of Calcification of Tissue Valves", Cardiol Clin., 3:385-396, 1985.

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