Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof
Patent
1993-12-16
1995-12-05
Nutter, Nathan M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acids and salts thereof
562400, 562508, 562510, 562512, 562519, C07C 5900, C07C 5906, C07C 5910, C07C 59105
Patent
active
054731038
ABSTRACT:
A monomeric diacid derivative includes at least two fatty acids coupled by a hydrolytically or enzymatically degradable bond. In a biological environment, the bond degrades forming naturally occurring fatty acid products thereby allowing elimination.
REFERENCES:
patent: 3290340 (1966-12-01), Wootton et al.
patent: 3360533 (1967-12-01), Wootton et al.
patent: 4757128 (1988-07-01), Domb et al.
patent: 5171812 (1992-12-01), Domb
Domb et al., 1993, "Polyanhydrides: Snythesis and Characterization", Adv. lymer Science 107:94-141.
Domb et al., 1992, "Degradable Polymers for Site-specific Drug Delivery", Polymers Adv. Techn. (August) 3:279-292.
Leong et al, 1986, "Bioerodible polyandrides as drug-carrier matrices" J. Biomed. Mat. Res. 20:51-64.
Domb and Langer, 1987, "Polyanhydrides. I. Preparation of High Molecular Weight Polyanhydrides", J. Polym. Sci. Part A: Polym. Chem. 25:3373-3386.
Ratcliff et al., 1984, "Preparation of evaluation of biodegradable polymeric systems for intra-articular delivery of drugs", J. Pharm. Pharmacol 36:431-436.
Laurencin et al, 1990, "Poly(anhydride) admin. in high doses in vivo: Studies of biocompatibility and toxicology", J. Biomed. Nat. Res. 24:1463-1481.
Brem et al., 1992, "Brain biocompatibility of a biodegradable controlled release polymer consisting of anhydride copolymer of fatty acid dimer and sebacic acid", J. Controlled Release 19:325-330.
Chasin et al, 1988, "Polyanhydrides for Controlled Drug Delivery" reprinted from Biopharm Manufacturing (February).
Domb Abraham J.
Nudelman Raphael
Nutter Nathan M.
Yissum Research Development Co. of the Hebrew University of Jeru
LandOfFree
Biopolymers derived from hydrolyzable diacid fats does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Biopolymers derived from hydrolyzable diacid fats, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biopolymers derived from hydrolyzable diacid fats will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1375264