Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure
Patent
1989-06-09
1995-05-09
Warden, Jill A.
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
A61K 3578
Patent
active
054137870
ABSTRACT:
Bioparyl is obtainable by a disclosed extraction hydrolysis and purification procedure applied to golden autumn leaves of the Gingko biloba tree. Bioparyl plays an important role in the regulation of the activity of certain enzymes, particularly ribonucleases (RNases), implicated in the fundamental mechanism of gene expression. It is low in or free from toxic or side effects in healthy animals, and can be used to ameliorate several pathogenic conditions. Bioparyl is effective in preventing or reversing fibrosis in various tissues, including the lungs and skin, engendered by radiation or chemotherapy. It reduces abnormally high concentrations of gamma-globulins and immuno-globulins found in certain inflammatory or auto-immune diseases, including Acquired Immune Deficiency Syndrome disease (AIDS). In patients with leukemia or solid cancers, Bioparyl normalizes the activity of ribonucleases.
REFERENCES:
patent: 4537774 (1985-08-01), Shimizu et al.
patent: 4571407 (1986-02-01), Chatterjee et al.
patent: 4886904 (1989-12-01), Tanaka et al.
Nakanishi, "The Ginkgolides", Pure and Applied Chemistry, 14, pp. 89-113 (1983).
Marshall S. G.
Plottel Roland
Warden Jill A.
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