Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2007-01-18
2010-11-16
Riley, Jezia (Department: 1637)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C536S023100, C536S024300, C536S025300
Reexamination Certificate
active
07833715
ABSTRACT:
Methods of binding biomolecules to a substrate are provided that include contacting the biomolecule with a branched linking moiety to form a branched linking structure. The branched linking structure is then contacted with a binding moiety on the substrate to form a coupled substrate binding structure, thereby binding the biomolecule to the substrate. The biomolecule may contain a Lewis base or a nucleophile to react with a Lewis acid or electrophile in the branched linking moiety. Alternatively, the biomolecule may contain a Lewis acid or electrophile that can react with a Lewis base or nucleophile in the branched linking moiety. Additionally, the biomolecule can be bound to the substrate through a covalent or non-covalent bond.
REFERENCES:
patent: 6130038 (2000-10-01), Becker et al.
patent: 6339147 (2002-01-01), Lukhtanov et al.
Greef Charles
Havens John R.
Onofrey Thomas J.
Schweitzer Markus
Wang Daguang
Murphy David B.
Nanogen Recognomics GmbH
O'Melveny & Myers LLP
Pang Diane K.
Riley Jezia
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