Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2006-11-14
2006-11-14
Ceperley, Mary E. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C436S531000, C530S402000, C530S408000, C530S409000, C530S410000, C530S411000, C530S811000
Reexamination Certificate
active
07135343
ABSTRACT:
The present invention relates to bio-molecule resistant surfaces for use in assays, particularly in assay devices such as arrays and microfluidic devices. The biomolecule resistant surface of the present invention are prepared by coating a substrate with hydrophilic terminated alkoxysilanes having formula (A):wherein R is an alkyl group of a size that allows for sufficient hydrolysis and n is 1, 2 or 3; R1is a hydrophilic moiety; LC is a C1to a C10linker chain consisting of a group selected from alkyl, aryl, alkaryl and aralkyl and m is 1, 2, or 3; R2is a C1to a C7alkyl group and x is 0, 1, or 2; and m+n+x is equal to 4.
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Gunther Janelle
Kim Namyong
Yang Dan-Hui
Agilent Technologie,s Inc.
Ceperley Mary E.
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