Biomolecule microarray support

Details Biomolecule microarray support Biomolecule microarray support

2004-12-31

2008-03-18

Lam, Ann Y. (Department: 1641)

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

Reexamination Certificate

active

07344877

ABSTRACT:
A biomolecule microarray support is comprised of a frame with upward projecting side walls. A transparent substrate is detachably positioned on the frame within the walls. A printed hydrophobic grid is arranged on the substrate for receiving spots of biomolecule samples. Each square on the grid is identified with a position number. A resilient gasket with an array of chambers is position on the substrate in alignment with the grid. The chambers are defined by dividing walls which are tapered from top to bottom. A clamping plate is positioned on the gasket which is received in stabilizing grooves under the clamping plate. Holes on the clamping plate aligned with the chambers allow a hybridization fluid to be introduced into the chambers. Fasteners connect the clamping plate and the frame to tightly compress the gasket against the substrate to seal the chambers from each other.

REFERENCES:
patent: 4450231 (1984-05-01), Ozkan
patent: 6168914 (2001-01-01), Campbell et al.
patent: 6464942 (2002-10-01), Coffman et al.

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