Biomaterials modified with superoxide dismutase mimics

Details Biomaterials modified with superoxide dismutase mimics Biomaterials modified with superoxide dismutase mimics

2000-05-26

2008-11-04

Isabella, David J (Department: 3774)

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

C623S023580, C514S054000, C514S055000, C530S400000, C536S053000

Reexamination Certificate

active

07445641

ABSTRACT:
The present invention relates to biomaterials modified with non-proteinaceous catalysts for the dismutation of superoxide, and processes for making such materials. This modification may be by covalent conjugation, copolymerization, or admixture of the non-proteinaceous catalysts with the biomaterial. The resulting modified biomaterials exhibit a marked decrease in inflammatory response and subsequent degradation when placed in contact with vertebrate biological systems.

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