Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2004-06-24
2011-10-11
Dunston, Jennifer (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091200, C536S024300, C536S024310
Reexamination Certificate
active
08034553
ABSTRACT:
The invention relates to the discovery that in chronic wounds the expression levels of certain genes are altered relative to the expression levels observed in healthy tissues.
REFERENCES:
patent: 3817837 (1974-06-01), Rubenstein et al.
patent: 3850752 (1974-11-01), Schuurs et al.
patent: 3939350 (1976-02-01), Kronick et al.
patent: 3996345 (1976-12-01), Ullman et al.
patent: 4036945 (1977-07-01), Haber
patent: 4275149 (1981-06-01), Litman et al.
patent: 4277437 (1981-07-01), Maggio
patent: 4331647 (1982-05-01), Goldenberg
patent: 4366241 (1982-12-01), Tom et al.
patent: 4376110 (1983-03-01), David et al.
patent: 5143854 (1992-09-01), Pirrung et al.
patent: 5723286 (1998-03-01), Dower et al.
patent: 5733731 (1998-03-01), Schatz et al.
patent: 5834432 (1998-11-01), Rodgers et al.
patent: 5846722 (1998-12-01), Kauvar et al.
patent: 5925523 (1999-07-01), Dove et al.
patent: 5928868 (1999-07-01), Liu et al.
patent: 5955280 (1999-09-01), Vidal et al.
patent: 6004746 (1999-12-01), Brent et al.
patent: 6096709 (2000-08-01), Rodgers et al.
patent: 6177407 (2001-01-01), Rodgers et al.
patent: 6294655 (2001-09-01), Ford et al.
patent: 6337072 (2002-01-01), Ford et al.
patent: 6344316 (2002-02-01), Lockhart et al.
patent: 6372892 (2002-04-01), Ballinger et al.
patent: 6444646 (2002-09-01), Rodgers et al.
patent: 6482800 (2002-11-01), Rodgers et al.
patent: 6524527 (2003-02-01), Fimreite et al.
patent: 6524795 (2003-02-01), Francis et al.
patent: 6541623 (2003-04-01), Ford et al.
patent: 6551785 (2003-04-01), Saverio di Giovine et al.
patent: 2003/0166069 (2003-09-01), Welcher et al.
patent: WO-90/15070 (1990-12-01), None
patent: WO-92/10092 (1992-06-01), None
patent: WO-93/09668 (1993-05-01), None
patent: WO-02/068579 (2002-09-01), None
patent: WO-2006/007254 (2006-01-01), None
Ishida, Y. et al. Absence of IL-1 Receptor Antagonist Impaired Wound Healing along with Aberrant NF-KB Activation and a Reciprocal Suppression of TGF-beta Signal Pathway, J. Immunol. 176:5598-5606, 2006.
Levy, B. How to Explain the Differences Between Renin Angiotensin System Modulators, Am J Hypertens. 18(9 Pt 2):134S-141S, 2005.
Lucentini, J. Gene Association Studies Typically Wrong, The Scientist 18(24):20, 2004.
Wu, T.D. Analysing Gene Expression Data from DNA Microarrays to Identify Candidate Genes, Journal of Pathology 195:53-65, 2001.
Chen, G. et al. Discordant Protein and mRNA Expression in Lung Adenocarcinomas, Molecular and Cellular Proteomics 1(4):304-13, 2002.
Fivenson, D.P. et al. Chemokine and Inflammatory Cytokine Changes During Chronic Wound Healing, Wound Repair and Regeneration 5(4):310-322, 1997.
Wang, X. et al. Interleukin-1 Receptor and Receptor Antagonist Gene Expression After Focal Stroke in Rats, Stroke 28(1):155-161, 1997.
Pusztai and Hess. Clinical trial design for microarray predictive marker discovery and assesment. Annals of Oncology, vol. 15, pp. 1731-1737, 2004.
Golub et al. Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring. Science, Bol. 286, pp. 531-537, Oct. 1999.
Takayanagi et al. Molecular cloning, sequence analysis and expression of cDNA encoding human type-1 angiotensin II receptor. Biochemical and Biophysical Research Communications vol. 183, No. 2, pp. 910-916, Mar. 1992.
Bigler et al. Interleukin-1 receptor antagonist production by human keratinocytes. The Journal of Investigative Dermatology, vol. 98, No. 1, pp. 38-44, Jan. 1992.
Yamada et al. Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1: structure, funciton, regulation of expression and chromosomal location. The Biochemical Journal vol. 302, pp. 781-790, Sep. 1994.
Cohen et al. Role of the angiotensin II type-2 receptor in radiation nephropathy. Translational Research: The Journal of Laboratory and Clinical Medicine vol. 150, No. 2, pp. 106-115, May 2007.
Cole et al. Early gene expression profile of human skin to injury using high-denisty cDNA microarrays. Wound Repair and Regeneration, vol. 9, No. 5, pp. 360-370, 2001.
GEO Accession No. GPL538 gene list for Research Genetics GF211 Microarray Filter, printed on Feb. 14, 2009 from http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GPL538, p. 1/71-71/71.
GenBank Accession No. H66070, GI: 1024810, publicly available Oct. 1995.
GenBank Accession No. T72877, GI: 689552, publicly available Mar. 1995.
GenBank Accession No. AA701976, GI: 2705089, publicly available Dec. 1997.
Jiang et al. 2001. Profiling Human Gene Expression with cDNA Microarrays. Current Protocols in Molecular Biology. 53:22.3.1- 22.3.26.
Hammerberg et al. Interleukin-1 receptor antagonist in normal and psoriatic epidermis. Journal of Clinical Investigation, vol. 90, pp. 571-583, Aug. 1990.
Haskill et al. cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proceedings of the National Academy of Science, USA, vol. 88, pp. 3681-3685, May 1991.
Cole et al. Human Genomics and Microarrays: Implications for the Plastic Surgeon. Plastic and Reconstructive Surgery, vol. 110, No. 3, pp. 849-858, Sep. 2002.
Hammerberg et al. Interleukin-1 receptor antagonist in normal and psoriatic epidermis. Journal of Clinical Investigation, vol. 90, pp. 571-583, Aug. 1992.
Bigler et al. Interleukin-1 receptor antagonist production by human keratinocytes. The Journal of Investigative Dermatology, vol. 98, No. 1, pp. 38-44, Jan. 1992.
Blackshaw et al. Type 3 inositol 1,4,5-tripphosphate receptor modulates cell death. The FASEB Journal, vol. 14, pp. 1375-1379, Jul. 2000.
Maranto, AR. Primary structure, ligand binding, and localization of the human type 3 inositol 1,4,5-triphosphate receptor expressed in intestinal epithelium. The Journal of Biological Chemistry, vol. 269, No. 2, pp. 1222-1230, Jan. 1994.
Rodgers et al. Development of angiotensin (1-7) as an agent to accelerate dermal repair. Wound Repair and Regeneration, vol. 9, No. 3, pp. 238-247, 2001.
Takayanagi et al. Molecular cloning, sequence analysis and expression of a cDNA encoding human type-1 angiotensin II receptor. Biochemical and Biophysical Research Communications, vol. 183, No. 2, pp. 910-916, Mar. 1992.
Joseph, S. K., “The Inositol Triphosphate Receptor Family”,Cellular Signalling, 8(1), (1996), 1-7.
Schroeder, R. A., et al., “Inhibition of the Inositol Triphosphate Receptor Increases Endotoxin-Mediated Nitric Oxide Synthesis in Macrophages”,Transplantation Proceedings, 29(6), (1997), 2569-2570.
Worley, P. F., et al., “Characterization of Inositol Trisphosphate Receptor Binding in Brain”,The Journal of Biological Chemistry, 262(25), (1987), 12132-12136.
“Partial International Search Report for corresponding PCT Application No. PCT/US2005/019151”, 3 pgs.
Arend, William P., et al., “Effects of Immune Complexes on Production by Human Monocytes of Interleukin 1 or an Interleukin 1 Inhibitor”,The Journal of Immunology, 134(6), (1985),3868-3875.
Barnett, Anthony H., “The Role of Angiotensin II Receptor Antagonists in the Management of Diabetes”,Blood Pressure, 10(Suppl 1), (2001),21-26.
Barringer, Kevin J., et al., “Blunt-End and Single-Strand Ligations byEscherichia coliLigase: Influence on an in vitro Amplification Scheme”,Gene, 89(1), (1990),117-122.
Bresnihan, Barry, “Treatment of Rheumatoid Arthritis With Recombinant Human Interleukin-1 Receptor Antagonist”,Arthritis&Rheumatism, 41(12), (1998),2196-2204.
Burnier, Michel, et al., “The Comparative Pharmacology of Angiotensin II Receptor Antagonists”,Blood Pressure, 10(Suppl. 1), (2001),6-11.
Carter, D. B., et al., “Purification, Cloning, Expression and Biological Characterization of an Interleukin-1 Receptor Antagonist Protein”,Nature, 344(6267), (1990),633-638.
Cohen, Stanley B., et al., “Interleukin 1 Receptor Antagonist Anakinra Improves Functional Status in Patients With Rheumatoid Arthritis”,The Journal of Rheumatology, 30(2), (2002),225-231.
Dinarello, Charles A., et al., “Multiple Biological Activities of Human Recombinant Int
Dority & Manning P.A.
Dunston Jennifer
Kimberly--Clark Worldwide, Inc.
LandOfFree
Biomarkers for wound healing does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Biomarkers for wound healing, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biomarkers for wound healing will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4284282