Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...
Reexamination Certificate
2005-11-30
2010-10-12
Bristol, Lynn (Department: 1643)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Structurally-modified antibody, immunoglobulin, or fragment...
C424S155100
Reexamination Certificate
active
07811562
ABSTRACT:
The present invention provides methods for identifying patients whose cancers are likely to be responsive to IGF1R inhibitory anti-cancer therapy along with methods for treating such patients. Patients identified by a method of the present invention can be treated with any of several known IGF1R inhibitory agents including antibodies, small molecule inhibitors and anti-sense nucleic acids.
REFERENCES:
patent: 4543439 (1985-09-01), Frackelton, Jr. et al.
patent: 5198340 (1993-03-01), Mukku
patent: 5262308 (1993-11-01), Baserga
patent: 5942412 (1999-08-01), Prager et al.
patent: 5958872 (1999-09-01), O'Connor et al.
patent: 5977307 (1999-11-01), Friden et al.
patent: 6022711 (2000-02-01), Cunningham et al.
patent: 6084085 (2000-07-01), Baserga et al.
patent: 6294330 (2001-09-01), Michnick et al.
patent: 6300129 (2001-10-01), Lonberg et al.
patent: 6316462 (2001-11-01), Bishop et al.
patent: 6333031 (2001-12-01), Olsson et al.
patent: 6346390 (2002-02-01), Olsson et al.
patent: 6372250 (2002-04-01), Pardridge
patent: 6537988 (2003-03-01), Lee
patent: 6645775 (2003-11-01), Clark et al.
patent: 7037498 (2006-05-01), Cohen et al.
patent: 7217796 (2007-05-01), Wang et al.
patent: 7326567 (2008-02-01), Saha
patent: 2002/0022023 (2002-02-01), Ullrich et al.
patent: 2002/0025313 (2002-02-01), Micklus et al.
patent: 2002/0107187 (2002-08-01), Kingston et al.
patent: 2002/0132275 (2002-09-01), Fidler et al.
patent: 2002/0155095 (2002-10-01), Nagabhushan et al.
patent: 2002/0164333 (2002-11-01), Nemerow et al.
patent: 2002/0169116 (2002-11-01), Kingston et al.
patent: 2002/0187925 (2002-12-01), Kingston et al.
patent: 2002/0197262 (2002-12-01), Hasan et al.
patent: 2003/0021780 (2003-01-01), Smith et al.
patent: 2003/0031658 (2003-02-01), Brodt et al.
patent: 2003/0045676 (2003-03-01), Kingston et al.
patent: 2003/0087342 (2003-05-01), Mermod et al.
patent: 2003/0088061 (2003-05-01), Staunton
patent: 2003/0092631 (2003-05-01), Deshayes et al.
patent: 2003/0138430 (2003-07-01), Stimmel et al.
patent: 2003/0165502 (2003-09-01), Fujita-Yamaguchi
patent: 2003/0195147 (2003-10-01), Pillutla et al.
patent: 2003/0235582 (2003-12-01), Singh et al.
patent: 2003/0236190 (2003-12-01), Pillutla et al.
patent: 2004/0009154 (2004-01-01), Khan et al.
patent: 2004/0009906 (2004-01-01), Kakkis et al.
patent: 2004/0018191 (2004-01-01), Wang et al.
patent: 2004/0023887 (2004-02-01), Pillutla et al.
patent: 2004/0047835 (2004-03-01), Bianco
patent: 2004/0057950 (2004-03-01), Waksal et al.
patent: 2004/0086503 (2004-05-01), Cohen et al.
patent: 2004/0086511 (2004-05-01), Zack et al.
patent: 2004/0102360 (2004-05-01), Barnett et al.
patent: 2004/0116330 (2004-06-01), Naito et al.
patent: 2004/0142381 (2004-07-01), Hubbard et al.
patent: 2004/0202651 (2004-10-01), Cohen et al.
patent: 2004/0228859 (2004-11-01), Graus et al.
patent: 2004/0265307 (2004-12-01), Singh et al.
patent: 2005/0008642 (2005-01-01), Graus et al.
patent: 2005/0048050 (2005-03-01), Fujita-Yamaguchi
patent: 2005/0069539 (2005-03-01), Cohen et al.
patent: 2005/0081812 (2005-04-01), Toedter et al.
patent: 2005/0084906 (2005-04-01), Goetsch et al.
patent: 2005/0136063 (2005-06-01), Wang et al.
patent: 2005/0176099 (2005-08-01), Saha
patent: 2005/0186203 (2005-08-01), Singh et al.
patent: 2005/0244408 (2005-11-01), Cohen et al.
patent: 2005/0249728 (2005-11-01), Singh et al.
patent: 2005/0249730 (2005-11-01), Goetsch et al.
patent: 2005/0272637 (2005-12-01), Clinton et al.
patent: 2005/0272755 (2005-12-01), Denis et al.
patent: 2005/0281812 (2005-12-01), Cohen et al.
patent: 2006/0018910 (2006-01-01), Gualberto et al.
patent: 2006/0205810 (2006-09-01), Zong et al.
patent: 2006/0233810 (2006-10-01), Wang et al.
patent: 2006/0233814 (2006-10-01), Goldmakher et al.
patent: 2006/0286103 (2006-12-01), Kolhe et al.
patent: 2007/0059241 (2007-03-01), Wang et al.
patent: 2007/0059305 (2007-03-01), Wang et al.
patent: 2007/0071675 (2007-03-01), Wu et al.
patent: 2008/0014197 (2008-01-01), Wang et al.
patent: 2008/0112888 (2008-05-01), Wang
patent: 197 19 001 (2001-05-01), None
patent: 2 834 900 (2003-07-01), None
patent: 2 834 990 (2003-07-01), None
patent: 2 834 991 (2003-07-01), None
patent: WO 91/04014 (1991-04-01), None
patent: WO 91/14438 (1991-10-01), None
patent: WO 97/44352 (1997-11-01), None
patent: WO98/17801 (1998-04-01), None
patent: WO 98/22092 (1998-05-01), None
patent: WO 98/45427 (1998-10-01), None
patent: WO 99/25378 (1999-05-01), None
patent: WO 99/28347 (1999-06-01), None
patent: WO 99/42127 (1999-08-01), None
patent: WO 99/60023 (1999-11-01), None
patent: WO 00/22130 (2000-04-01), None
patent: WO 00/50067 (2000-08-01), None
patent: WO 00/69454 (2000-11-01), None
patent: WO 01/07084 (2001-02-01), None
patent: WO 01/30964 (2001-05-01), None
patent: WO 01/36632 (2001-05-01), None
patent: WO 01/70268 (2001-09-01), None
patent: WO 01/70930 (2001-09-01), None
patent: WO 01/72771 (2001-10-01), None
patent: WO 01/75064 (2001-10-01), None
patent: WO 02/04522 (2002-01-01), None
patent: WO 02/07783 (2002-01-01), None
patent: WO 02/27017 (2002-04-01), None
patent: WO 02/31500 (2002-04-01), None
patent: WO 02/43758 (2002-06-01), None
patent: WO 02/053596 (2002-07-01), None
patent: WO 02/054066 (2002-07-01), None
patent: WO 02/072780 (2002-09-01), None
patent: WO 2004/087756 (2002-10-01), None
patent: WO 02/088752 (2002-11-01), None
patent: WO 02/092599 (2002-11-01), None
patent: WO 02/102854 (2002-12-01), None
patent: WO 02/102972 (2002-12-01), None
patent: WO 02/102973 (2002-12-01), None
patent: WO 03/000928 (2003-01-01), None
patent: WO 03/14696 (2003-02-01), None
patent: WO 03/027246 (2003-04-01), None
patent: WO 03/039538 (2003-05-01), None
patent: WO 03/059951 (2003-07-01), None
patent: WO 03/088910 (2003-10-01), None
patent: WO 03/100008 (2003-12-01), None
patent: WO 03/100059 (2003-12-01), None
patent: WO 03/106621 (2003-12-01), None
patent: WO 03/106621 (2003-12-01), None
patent: WO 2004/030625 (2004-04-01), None
patent: WO 2004/030627 (2004-04-01), None
patent: WO 2004/056865 (2004-07-01), None
patent: WO 2004/071529 (2004-08-01), None
patent: WO 2004/083248 (2004-09-01), None
patent: WO2004/096224 (2004-11-01), None
patent: WO2004/096224 (2004-11-01), None
patent: WO 2005/005635 (2005-01-01), None
patent: WO 2005/016967 (2005-02-01), None
patent: WO 2005/016970 (2005-02-01), None
patent: WO2005/052005 (2005-06-01), None
patent: WO 2005/061541 (2005-07-01), None
patent: WO2005/117980 (2005-12-01), None
patent: WO2006/013472 (2006-02-01), None
patent: WO2006069202 (2006-06-01), None
patent: WO2006/020258 (2006-12-01), None
patent: WO2007/093008 (2007-08-01), None
Tonini et al. (Curr. Pharm. Design 12:2303-2317 (2006)).
Leventhal et al. (Exp. Cell. Res. 221:179-186 (1995)).
Singleton et al. (Can. Res. 56:4522-4529 (1996)).
Maloney et al. (Can. Res. 63:5073-5083 (2003)).
Jain, Scientific American Jul. 1994 pp. 58-65.
Chatterjee et al., Cancer Immunol. Imunother., 38:75-82, 1994.
Dermer, Biotechnology 12: 320, 1994.
Gura et al., Science vol. 278:1041-1042 (Nov. 1997).
Seaver, 1994; Genetic Engineering vol. 14(14):10 and 21.
Rudikoff et al., Proc Natl Acad Sci USA 1982 vol. 79 p. 1979.
Casset et al. (2003) BBRC 307, 198-205.
Vajdos et al. (2002) J. Mol. Biol. 320, 415-428.
Holm et al., Mol. Immunol. 44, 1075-1084, 2007.
Sequence search alignment for SEQ ID Nos. 2, 4, 6, 8, 10 and 12 against US 20040018191 (Wang et al.), pp. 1-6.
Sequence search alignment for SEQ ID Nos. 2, 4, 6, 8, 10 and 12 against US 20070059241 (Wang et al.), pp. 1-6.
Sequence search alignment for SEQ ID Nos. 2, 4, 6, 8, 10 and 12 against US 20070059305 (Wang et al.), pp. 1-6.
Sequence search alignment for SEQ ID Nos. 8 and 10 against US 20050136063 (Wang et al.), pp. 1-2.
Sequence search alignment output for SEQ ID No. 13 (see Cohen et al. US 20040202651) pp. 1-3.
Sequence search alignment output for SEQ ID No. 14 (see Cohen et al. US 20040202651) pp. 1-5.
Sequence search alignment output for SEQ ID No. 15 (see Cohen et al. US 20040202651) pp. 1-3.
Sequence search alignment output for SEQ ID No. 19 (see Cohen et al. US 20040202651) pp. 1-5.
Dennis (Nature 442:739-741 (2006
Liu Ming
Pachter Jonathan A.
Wang Yan
Wang Yaolin
Bristol Lynn
Schering Corporation
LandOfFree
Biomarkers for pre-selection of patients for anti-IGF1R therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Biomarkers for pre-selection of patients for anti-IGF1R therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biomarkers for pre-selection of patients for anti-IGF1R therapy will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4181221