Biomarkers for chronic transplant dysfunction

Details Biomarkers for chronic transplant dysfunction Biomarkers for chronic transplant dysfunction

2011-08-16

2011-08-16

Cheu, Jacob (Department: 1641)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

C435S007200, C436S518000

Reexamination Certificate

active

07998687

ABSTRACT:
The invention relates to the analysis and identification of genes that are modulated in transplant rejection. This alteration of gene expression provides a molecular signature to accurately detect transplant rejection.

REFERENCES:
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patent: 2004/074815 (2004-09-01), None
Racusen L.C. et al., “The banff 97 working classification of renal allograft pathology”, Kidney International, vol. 55, pp. 713-723, (1999).
Nankivell B.J. et al., “The natural history of chronic allograft nephropathy”, The New England Journal of Medicine, vol. 349, No. 24, pp. 2326-2333, (2003).

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