Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-08-02
2005-08-02
LeGuyader, John L. (Department: 1635)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100, C435S091200, C435S091210, C536S023100, C536S024300, C536S024310, C536S024330, C536S023500
Reexamination Certificate
active
06924099
ABSTRACT:
The present invention relates to carcinogenesis biomarkers produced by phenobarbital-treated rat hepatocytes, nucleic acid molecules that encode carcinogenesis biomarkers or a fragment thereof and nucleic acid molecules that are useful as probes or primers for detecting or inducing carcinogenesis, respectively. The invention also relates to applications of the factor or fragment such as forming antibodies capable of binding the carcinogenesis biomarkers or fragments thereof.
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Norman H. Lee et al., Comparative expressed-sequence-tag analysis of differential gene expression profiles in PC-12 cells before and after nerve growth factor treatment, Proc. Natl. Acad. Sci. USA, vol. 92, pp. 8303-8307 (1995).
Bunch Roderick T
Curtiss Sandra W.
Morris Dale L
Rodi Charles P.
G.D. Searle & Co.
Harness Dickey & Pierce PLC
LeGuyader John L.
Zara Jane
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