Biomarker generator

Radiant energy – Irradiation of objects or material – Ion or electron beam irradiation

Reexamination Certificate

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Details

C376S190000, C376S195000, C376S198000

Reexamination Certificate

active

08080815

ABSTRACT:
An improved biomarker generator and a method suitable for efficiently producing short lived radiopharmaceuticals in quantities on the order of a unit dose. The improved biomarker generator includes a particle accelerator and a radiopharmaceutical micro-synthesis system. The micro-accelerator of the improved biomarker generator is optimized for producing radioisotopes useful in synthesizing radiopharmaceuticals in quantities on the order of one unit dose allowing for significant reductions in size, power requirements, and weight when compared to conventional radiopharmaceutical cyclotrons. The radiopharmaceutical micro-synthesis system of the improved biomarker generator is a small volume chemical synthesis system comprising a microreactor and/or a microfluidic chip and optimized for synthesizing the radiopharmaceutical in quantities on the order of one unit dose allowing for significant reductions in the quantity of radioisotope required and the processing time when compared to conventional radiopharmaceutical processing systems.

REFERENCES:
patent: 5037602 (1991-08-01), Dabiri et al.
patent: 7394081 (2008-07-01), Okazaki et al.
patent: 2004/0046116 (2004-03-01), Schroeder et al.
patent: 2006/0049902 (2006-03-01), Kaufman
patent: 2008/0067413 (2008-03-01), Nutt
patent: 2008/0258653 (2008-10-01), Nutt
patent: 2009/0218520 (2009-09-01), Nutt

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