Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1997-11-25
2000-09-12
Chin, Christopher L.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
422 55, 422 57, 422 58, 422 8201, 422 8205, 422 8206, 422 8207, 422 8208, 435 6, 435 732, 4352871, 4352872, 4352887, 435808, 436518, 436524, 436525, 436531, 436805, G01N 3353
Patent
active
061176435
ABSTRACT:
Disclosed are monolithic bioelectronic devices comprising a bioreporter and an OASIC. These bioluminescent bioreporter integrated circuit are useful in detecting substances such as pollutants, explosives, and heavy-metals residing in inhospitable areas such as groundwater, industrial process vessels, and battlefields. Also disclosed are methods and apparatus for environmental pollutant detection, oil exploration, drug discovery, industrial process control, and hazardous chemical monitoring.
REFERENCES:
patent: 5770389 (1998-06-01), Ching et al.
patent: 5834218 (1998-11-01), Gremillet
International Search Report dated Apr. 13, 1999 (PCT/US98/25295;4310.002510).
Simpson et al., "Bioluminescent-bioreporter integrated circuits form novel whole-cell biosensors," TIBTECH16:332-338, 1998.
Webb et al., "Kinetics and repsonse of Pseudomonas fluorescens HK44 biosensor," Biotechnology & Bioengineering, 54(5):491-502, 1997.
Ahluwalia, De Rossi, Ristori, Schirone, Serra, "A comparative study of protein immobilization techniques for optical immunosensors," Biosensors and Bioelectronics, 7:207-214, 1991.
Alvarez-Icaza and Bilitewski, "Mass production of biosensors," Anal. Chem., 65:525A-533A, 1993.
Anis, Wright, Rogers, Thompson, Valdes, Eldefrawi, "A fiber-optic immunosensor for detecting parathion," Anal. Lett., 25:627-635, 1992.
Arnold, "Fibre-optic biosensors," J. Biotechnol., 15:219-228, 1990.
Bluestein and Chen, "Rapid response fiber optic evanescent wave immunosensors," Immunol. Ser., 53:145-170, 1990.
Blum, Gautier, Coulet, "Design of luminescence photobiosensors," J. Biolumin. Chemilumin., 4:543-550, 1989.
Chee, Yang, Hubbell, Berno, Huang, Stern, Winkler, Lockhart, Morris, Fodor, "Accessing genetic information with high-density DNA arrays," Science, 274:610-614, Oct. 1996.
Fodor, Rava, Huang, Pease, Holmes, Adams, "Multiplexed biochemical assays with biological chips," Nature, 364:555-556, Aug. 1993.
Grate, Martin, White, "Acoustic wave microsensors," Part 2, Anal. Chem., 65:987A-996A, 1993.
Griffiths and Hall, "Biosensors--What real progress is being made?" Trends Biotechnol., 11:122-130, 1993.
Hacia, Brody, Chee, Fodor, Collins, "Detection of heterozygous mutations in BRCA1 using high density oligonucleotide arrays and two-colour fluorescence analysis," Nature Genetics, 14:441-447, Dec. 1996.
Hacia, Makalowski, Edgemon, Erdos, Robbins, Fodor, Brody, Collins, "Evolutionary sequence comparisons using high-density oligonucleotide arrays," Nature Genetics, 18:155-158, Feb. 1998.
Herrero, de Lorenzo, Timmis, "Transposon vectors containing non-antibiotic resistance selection markers for cloning and stable chromosomal insertion of foreign genes in gram-negative bacteria," J. Bacteriol., 172:6557-6567, 1990.
Hill, Urwin, and Crampton, "A comparison of non-radioactive labeling and detection systems with synthetic oligonucleotide probes for the species identification of mosquitoes in the Anopheles gambiae complex," Am. J. Trop. Med. Hyg., 44(6):609-622, 1991.
Janata, Principles of Chemical Sensors, Plenum Press, New York, 1989.
Kauffman and Guilbault, "Enzyme electrode biosensors: theory and applications," Bioanal. Appl. Enzymes., 36:36-113, 1992.
Lee and Thompson, "Fibre optic biosensor assay of Newcastle Disease Virus," J. Immunol. Methods, 166(1):123-131, 1993.
Lipshutz, Morris, Chee, Hubbell, Kozal, Shah, Shen, Yang, Fodor, "Using oligonucleotide probe arrays to access genetic diversity," Biotechniques, 19(3):442-447, 1995.
Mrksich and Whitesides, "Patterning self-assembled monolayers using microcontact printing: a new technology for biosensors," Trends Biotechnol., 13:228-235, 1995.
Pease, Solas, Sullivan, Cronin, Holmes, Fodor, "Light-generated oligonucleotide arrays for rapid DNA sequence analysis," Proc. Natl. Acad. Sci. USA, 91:5022-5026, May 1994.
Ogert, Brown, Singh, Shriver-Lake, Ligler, "Detection of Chostridium botulinum toxin A using a fibre optic based biosensor," Anal. Biochem., 205:306-312, 1992.
Swain, "Biosensors: a new realism," Ann. Biol. Clin. (Paris), 50:175-179, 1992.
Wingard, "Biosensor trends," Ann. NY Acad. Sci., 613:44-53, 1990.
Wood and Gruber, "Transduction in microbial biosensors using multiplexed bioliminescence," Biosensors & Bioelectronics, 11(3)207-214, 1996.
Paulus Michael J.
Sayler Gary S.
Simpson Michael L.
Chin Christopher L.
The University of Tennessee Research Corp.
U-T Battelle, LLC
LandOfFree
Bioluminescent bioreporter integrated circuit does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Bioluminescent bioreporter integrated circuit, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Bioluminescent bioreporter integrated circuit will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-94523