Bioluminescent assays and bacterial strains useful therein

Details Bioluminescent assays and bacterial strains useful therein Bioluminescent assays and bacterial strains useful therein

2005-10-18

2005-10-18

Wessendorf, T. D. (Department: 1639)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C435S173300, C435S173300, C435S235100, C536S023400

Reexamination Certificate

active

06956113

ABSTRACT:
The present invention relates to novel assays for assessing the degree to which a cell is metabolically active. Also provided, are mutagenicity assays and, more specifically, methods for determining whether a given agent is genotoxic. Embodiments of the assays employ a microorganism, or a mammalian cell, that has been genetically modified to produce light when the presence of test agent results in a mutation, e.g., reversion or forward, in the DNA of such microorganism or cell.

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