Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1984-02-17
1987-05-12
Marantz, Sidney
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
436501, 436536, 436544, 436547, 436172, 435 8, 530802, G01N 3353, G01N 33566, G01N 33536, G01N 33532
Patent
active
046650229
ABSTRACT:
Reagent for immunoassay, ligand binding assay and ligand receptor assay in which luciferin is covalently bonded to a molecule having biological activity for bonding to a particular biologically active group of a material and method in which the luciferin and biologically active molecule conjugate is added to a material having a group for combination with the biological activity of the conjugated molecule, the mixture is incubated to bond the material to the reagent through the biological activity and the product of the bonding is reacted with luciferase to produce bioluminescence having intensity dependent on the concentration of the material being assayed.
REFERENCES:
patent: 4104029 (1978-08-01), Maier, Jr.
patent: 4232119 (1980-11-01), Carlsson et al.
White, E. H. et al., (1965) J. Org. Chem. 30:2344-2348.
Hsueh Aaron J.
Schaeffer James M.
Marantz Sidney
Spiegel Jack
The Regents of the University of California
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