Biologically stabilized compositions comprising collagen as the

Details Biologically stabilized compositions comprising collagen as the Biologically stabilized compositions comprising collagen as the

1981-07-20

1983-06-14

Welsh, Maurice J.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

351160H, 523108, 523449, 524 21, 524 23, 524704, 525937, C08H 100

Patent

active

043884288

ABSTRACT:
Biologically stabilized compositions are prepared by subjecting to polymerization conditions an aqueous admixture comprising from 50 to about 70 weight percent solubilized collagen and from about 30 to less than 50 weight percent of an organic compound which is characterized by a polymerizable ethylenic group (>C.dbd.C<) as illustrated by N,N-dimethylacrylamide, 2-hydroxyethyl methacrylate, dimethylaminoethyl methacrylate or methoxytriethylene glycol methacrylate. The reactants employed are at least partially soluble in the aqueous reaction medium. The hydrogels thus prepared can be in the form of novel shaped articles having utility in the medical and cosmetic fields. Such hydrogels exhibit good biological stability, high water content, high oxygen permeability and sufficient mechanical strength characteristics to be useful as contact lenses.

REFERENCES:
patent: 4035330 (1977-07-01), Schultz
patent: 4223984 (1980-09-01), Miyata et al.
patent: 4252421 (1981-02-01), Foley
patent: 4260228 (1981-04-01), Miyata
patent: 4264155 (1981-04-01), Miyata
patent: 4264493 (1981-04-01), Battista
patent: 4268131 (1981-05-01), Miyata et al.

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