Biologically relevant methods for the rapid determination of ste

Details Biologically relevant methods for the rapid determination of ste Biologically relevant methods for the rapid determination of ste

1995-01-30

1996-01-23

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 4, 435 25, 435 26, 435 29, 4352874, 435810, 435832, 435842, 435920, 422 58, 422 61, 422 86, 422 88, 422102, 206528, 206530, 206534, C12Q 122, G01N 2100

Patent

active

054864593

ABSTRACT:
The invention is directed to biological processes and apparatus for determining the efficacy of a sterilization cycle based upon the recovery of activity of interactive enzyme systems comprising enzymes, coenzymes, catalysts, cofactors, substrates or any other necessary reagents. The invention provides a vital process for expediting sterility verification before utilization of the articles thought to be sterilized. The invention involves the rapid detection of any surviving interactive enzymatic activity which directly relates to the probability of any biological spores surviving in a test sample. An absence of a change indicates that the sterilization process had inactivated the enzyme system thereby preventing the interactive reaction from taking place which is a rapid equivalent to directly detecting the survivability of bacterial spores in a similar test. The methods and apparatus of the invention are useful in the health care industry such as in hospitals, laboratories, and research institutions, in food and environmental technology, and in all technologies which utilize sterilization in manufacturing, production or waste disposal.

REFERENCES:
patent: 2606654 (1945-04-01), Davis et al.
patent: 3239429 (1963-02-01), Menolasino et al.
patent: 3440144 (1965-05-01), Andersen
patent: 3981683 (1976-09-01), Larsson et al.
patent: 4001587 (1977-01-01), Panchenkov et al.
patent: 4038873 (1977-08-01), Kimmel
patent: 4155895 (1979-05-01), Rohowetz et al.
patent: 4388233 (1983-06-01), Bissell et al.
patent: 4448548 (1984-05-01), Foley
patent: 4596773 (1986-06-01), Wheeler, Jr.
patent: 4663287 (1987-05-01), Barker
patent: 4717661 (1988-01-01), McCormick et al.
patent: 4732850 (1988-03-01), Brown et al.
patent: 4741437 (1988-05-01), Gorski et al.
patent: 4885253 (1989-12-01), Kralovic
patent: 5073488 (1991-12-01), Matner et al.
patent: 5167923 (1992-12-01), Van Iperen
patent: 5223401 (1993-06-01), Foltz et al.
patent: 5252484 (1993-10-01), Matner et al.

Affiliated with

Also associated with

Rating

Biologically relevant methods for the rapid determination of ste does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biologically relevant methods for the rapid determination of ste, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biologically relevant methods for the rapid determination of ste will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1504661