Biologically pure culture of mutant mycobacterium

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435863, C12N 120

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active

043395392

ABSTRACT:
Mutants which are used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to androsta-1,4-diene-3,17-dione (ADD) and androst-4-ene-3,17-dione (AD). ADD and AD are valuable intermediates to make useful steroids.

REFERENCES:
patent: 3388042 (1968-06-01), Arima et al.
patent: 3623954 (1971-11-01), Kieslich et al.
Lamanna et al., Basic Bacteriology, 3rd Ed., The Williams & Wilkins Co., pp. 723-727, (1965).
Metzler, Biochemistry, The Chemical Reaction of Living Cells, Academic Press, Inc., pp. 945 & 946, (1977).

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