Biologically pure culture of Actinoplanes missouriensis

Details Biologically pure culture of Actinoplanes missouriensis Biologically pure culture of Actinoplanes missouriensis

1981-10-09

1983-03-01

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Using actinomycetales

435827, C12P 106, C12R 1045

Patent

active

043755135

ABSTRACT:
Antibiotic A-4696 factors B.sub.1, B.sub.2, B.sub.3, C.sub.1a, C.sub.3, and E.sub.1 are isolated from antibiotic A-4696, the latter being produced by Actinoplanes missouriensis strains ATCC 31680, ATCC 31682, and ATCC 31683 under submerged aerobic conditions in a culture medium and isolated from the fermentation broth by absorption on an ion exchange resin and eluted therefrom at p.sup.H 10.5 with sodium hydroxide. The novel factors are separated by thin layer chromatography and high pressure liquid chromatography and have antimicrobial and growth promotant activity.

REFERENCES:
patent: 3952095 (1976-04-01), Hamill et al.
patent: 4064233 (1976-12-01), Hamill et al.
patent: 4115552 (1978-09-01), Hamill et al.
patent: 4239751 (1980-12-01), Coronelli et al.
patent: 4303646 (1981-12-01), Cavalleri et al.

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