Biologically active surface ceramic and process for producing th

Details Biologically active surface ceramic and process for producing th Biologically active surface ceramic and process for producing th

1991-04-18

1991-12-10

Group, Karl

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Bone

501 1, 106 35, A61F 228

Patent

active

050714341

ABSTRACT:
A biologically active ceramic suitable as a substitute for hard tissues in a living body is disclosed, comprising a dense calcium phosphate ceramic body having formed thereon a surface layer mainly comprising at least one of hydroxyapatite and calcium tertiary .beta.-phosphate and having a surface roughness of from 10 to 1000 .mu.m. The surface layer is formed by forming a calcium phosphate coating containing hydroxyapatite and a phosphate or phosphate-containing glass capable of reacting with hydroxyapatite to form calcium tertiary phosphate on a calcium phosphate molded article or a sintered body thereof and calcining the calcium phosphate molded or sintered body with the calcium phosphate coating at a temperature of from 700.degree. to 1350.degree. C. to allow a part or the whole of the hydroxyapatite to react to form calcium tertiary .beta.-phosphate. The ceramic has improved bioaffinity and sufficient mechanical strength, and can be integrated into hard tissues in a reduced period of time.

REFERENCES:
patent: 4976736 (1990-12-01), White et al.
patent: 4988362 (1991-01-01), Toriyama et al.
patent: 5017518 (1991-05-01), Hirayama et al.

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