Biologically active substance, process for preparing the substan

Details Biologically active substance, process for preparing the substan Biologically active substance, process for preparing the substan

1983-12-09

1986-11-04

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 68, 435947, 530395, 424 88, 514 8, C12P 2106, C12R 190, A61K 3900, A61K 3700

Patent

active

046210547

ABSTRACT:
This invention relates to a biologically active substance which is a glycoprotein having a molecular weight of 3,000 to 5,000 and has activity to inhibit toxoplasma multiplication in homologous cells and heterologous cells.
This invention also relates to a process for preparing the substance, immunoactive compositions containing the substance and use of the substance as a drug.

REFERENCES:
Howard et al., vol. 94, Chem. Abst. No. 28377t, 1980, "Characterization of Surface Protein and Glycoproteins on Red Blood Cells from Mice Infected with Hemosporidia: Babesia rodhaini Infections of BALB/c Mice.
James et al., Infect Immun. vol. 31(1) pp. 358-361, "Isolation and Partial Characterization of Culture Derived Soluble Babesia Bovis Antigens".
Miller et al., Chem. Abst vol. 84, No. 17778v, 1976, "Enzymatic Modification of the Erythrocyte Membrane Surface and its Effect on Malarial Merozoite Invasion".
Suzuki et al., Chem Abst No. 30319t, vol. 79 "Toxoplasma Gondii, Trypsin Treatment of Trophozoites For Enhanced Immune Cytolysis in the Dye Test, 1973.
Cunliffe et al., Chem Abst No. 20346v "Effects of Bromelain and Pronase on Erythrocyte Membranes", p. 509.

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