Biologically active substance

Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure

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435171, A61K 3572, C12P 102

Patent

active

050009532

ABSTRACT:
A novel biologically active substance named Islets-Activating Protein obtained from the cultivation of the miocroorganism Bordetella and having insulin secretion promoting action as well as glucose tolerance improving action for mammals.

REFERENCES:
Bergery's Manual of Determinative Bacteriology, vol. 8, pp. 282-283 (1974).
"Cell-Envelope Proteins of Bordetella pertussis", Parton et al., J. Med. Microbiol., vol. 8, pp. 47-56 (1975).
The American Type Culture Collection, Catalog of Strains, p. 19 (1970).
Morse et al., J. of Experimental Medicine, vol. 143, 1976, pp. 1483-1502.
Lehrer et al, J. of Immunology, vol. 113, No. 1, 7/74, pp. 18-27.
Arai et al., Biochimica et Biophysica Acta, 444, 1976, 765-782.
Chemical Abstracts, 71: 68911(u) (1969).

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