Biologically active rupununines

Details Biologically active rupununines Biologically active rupununines

1994-02-01

1996-10-29

Kight, John

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514 82, 514281, 514841, 514895, 514918, A61K 3578, A61K 31675

Patent

active

055694560

ABSTRACT:
A rupununine, either in purified form or a derivative in which one or both of the hydroxyl groups is substituted, the rupununine having the formula: ##STR1## where R.dbd.--H or --CH.sub.3.

REFERENCES:
patent: 5162331 (1992-11-01), Staub et al.
Cava et al. J. Org. Chem., vol. 39(24), pp. 3588-3590, (1974).
Tackie et al. Phytochemistry, vol. 19(8), pp. 1882-1883, (1980).
Berthou et al. Tetrahedron, vol. 44(8), pp. 2193-2201, (1988).
Marshall et al. Antimicrob. Agents Chemother. vol. 38(1), pp. 96-103, (1994 Jan.).
Tetrahedron Letters No. 27, 1975, Oxford GB pp. 2249-2252 Shamma et al "A controlled oxidaiton of bisbenzylisoquinolines".
J. of Organic Chemistry vol. 39, No. 24, 1974, Easton U.S. pp. 3588-3591 Cava et al "Phlebicine, a new biphanylbisbenzylisoquinoline alkaloid from Cremastosperma polyphlebum".

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