Biologically active reagents prepared from carboxy-containing po

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving virus or bacteriophage

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422 56, 422 57, 422 58, 422 61, 436170, 436805, 436532, 436533, 436534, 436531, 435 6, 435 722, 435 731, 435 732, 428403, 428407, 5263171, 5263184, 526314, 526286, G01N 33545, G01N 33546

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active

051477777

ABSTRACT:
Biologically active reagents are prepared from particles of copolymers having highly reactive carboxy or equivalent groups. The reagents are prepared by covalently attaching biologically active substances, for example antibodies, to the particles, directly or indirectly through highly reactive carboxy groups on the particle surface. These reagents are used to advantage in analytical elements, methods for the detection of specific binding ligands (such as immunological species) and immunoassays, and in purification methods as affinity chromatography reagents.

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