Biologically active reagent prepared from aldehyde-containing po

Details Biologically active reagent prepared from aldehyde-containing po Biologically active reagent prepared from aldehyde-containing po

1992-10-01

1995-03-28

Ceperley, Mary E.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 793, 435 794, 436501, 436533, 436534, 530413, G01N 33546

Patent

active

054016339

ABSTRACT:
A biologically active reagent is prepared by reacting a biologically active substance covalently to a polymeric particle having pendant aldehyde groups. Such groups are provided by a polymerizable monomer represented by the structure: ##STR1## wherein Ar is arylene, R and R.sup.1 are independently hydrogen, halo or lower alkyl, R.sup.2 and R.sup.3 are independently alkylene of 1 to 4 carbon atoms in the chain, R.sup.4 is arylene, m is 0 or 1, and n is an integer of 1 to 4. These reagents can be used in a variety of specific binding and affinity purification methods, and in both solution assays and dry analytical elements.

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