Biologically active porcine somatotropin polypeptides and method

Details Biologically active porcine somatotropin polypeptides and method Biologically active porcine somatotropin polypeptides and method

1992-07-29

1994-08-16

Hill, Jr., Robert J.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

Hormones, e.g., prolactin, thymosin, growth factors, etc.

530300, 530324, A61K 3702, A61K 3736, C07K 700, A01N 3718

Patent

active

053388364

ABSTRACT:
An isolated polypeptide corresponding to the epitope of porcine somatotropin is provided by this invention as well as methods of enhancing the growth of an animal by administering to the animal this polypeptide in compositions.

REFERENCES:
Aston et al. 1991 Mol. Immunol. 28:41-50.
Aston et al. 1986 J. Endocr. 110:381.
Bates et al. 1992 (Marel) 132: 369-375.
Aston et al. 1987 Mol. Immunol. 24:143-150.
Wang et al. 1990 J. Endocr. 127:481-485.
Hughes et al., The Nature and Regulation of the Receptors for Pituitary Growth Hormone, Ann. Rev. Physiol., 47:469-482 (1985).
Pell et al., Active Immunization with a Synthetic Peptide Region of Growth Hormone: Increased Lean Tissue Growth, Journal of Endocrinology, 131:R1-R4 (1991).
Abdel-Meguid et al., Three-Dimensional Structure of a Genetically Engineered Variant of Porcine Growth Hormone, Proc. Natl. Acad. Sci. USA, 84:6434-6437 (1987).

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