Biologically active peptides from functional domains of...

Details Biologically active peptides from functional domains of... Biologically active peptides from functional domains of...

2006-05-16

2006-05-16

Carlson, Karen Cochrane (Department: 1653)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S300000, C530S324000, C530S325000, C530S326000

Reexamination Certificate

active

07045500

ABSTRACT:
The present invention provides peptides having an amino acid sequence that is the amino acid sequence of a human bactericidal/permeability-increasing protein (BPI) functional domain or a subsequence thereof, and variants of the sequence or subsequence thereof, having at least one of the BPI biological activities, such as heparin binding, heparin neutralization, LPS binding, LPS neutralization or bactericidal activity. The invention provides peptides and pharmaceutical compositions of such peptides for a variety of therapeutic uses.

REFERENCES:
patent: 5733872 (1998-03-01), Little
patent: 5763567 (1998-06-01), Little

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