Biologically active peptides and their use for repairing...

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S009100

Reexamination Certificate

active

07741436

ABSTRACT:
The present invention relates to biologically active peptides derived from the neurite outgrowth-promoting domain of laminin-1, i.e. the γ1-chain of laminin-1. These peptides include the decapeptide RDIAEIIKDI (SEQ ID NO: 1) and the truncated peptides derived therefrom comprising the biologically active domain thereof, the tripeptide KDI. The invention is directed to the biologically active tripeptide motif KDI, and to its use in promoting regeneration of neuronal or non-neuronal tissues and, in specific, to its use in the treatment of spinal cord injuries.

REFERENCES:
patent: 3590722 (1971-07-01), Leptrone
patent: 3645756 (1972-02-01), Huth et al.
patent: 5780090 (1998-07-01), Frerot et al.
patent: 2002/0168718 (2002-11-01), Hubbell et al.
patent: 20010297 (2000-10-01), None
patent: 0 067 425 (1982-12-01), None
patent: 2 284 422 (1995-06-01), None
patent: WO-93/24155 (1993-12-01), None
patent: WO-9324155 (1993-12-01), None
patent: WO-94/04560 (1994-03-01), None
patent: WO-98/43686 (1998-10-01), None
patent: WO-98/45325 (1998-10-01), None
patent: WO-9843686 (1998-10-01), None
patent: WO-99/00418 (1999-01-01), None
patent: WO-9900418 (1999-01-01), None
patent: WO-01/66164 (2001-09-01), None
Guo et al., PNAS, 101(25):9205-9210, 2004.
Kasai et al., Biochemistry, 46:3966-3974, 2007.
Fahy et al. Anesthesiol Clin North America, 20(2):441-462, 2002.
Liesi, Paivi et al., Journal of Neuroscience Research, vol. 66, 2001, pp. 1047-1053.
Liesi, Paivi et al., FEBS Lett., vol. 224, No. 1, 1989, pp. 141-148.
T. Serafini et al., Cell. 1994, Aug. 12: 78(3) :409-24; PubMed Abstract ID:8062384.
P. Liesi et al., Journal of Neuroscience Research, 40:199-206 (1995).
M. Matsuzawa et al., Int. J. Devl. Neuroscience, vol. 14, No. 3, pp. 283-295, 1996.
M. Matsuzawa et al., Journal of Neuroscience Research, 53:114-124 (1998).
J. Meyerhardt et al., Cell Growth & Differentiation, vol. 10, 35-42, Jan. 1999.
Eric Guadango et al., GLIA 47: pp. 138-149 (2004)..
Ron Liebkind et al., Journal of Neuroscience Research 73: pp. 637-643 (2003).
P. Liesi, Experientia 46 (1990).
Paivi Liesi et al., Journal of Neuroscience Research 64: pp. 144-167 (2001).
Paivi Liesi et al., Journal of Neuroscrence Research 66: pp. 1047-1053 (2001).
Paivi Liesi et al., Experiemental Neurology 173: pp. 31-45 (2002).
S. Murtomaki et al., Jburnal of Neuroscience Research 32: pp. 261-273 (1992).
Hiroshi Nishimune et al., Nature Publishing Group vol. 432, pp. 580-587, Dec. 2, 2004.
Edouard Palu et al., Journal of Neuroscience Research 69: 243-256 (2002).
Arja Pasternack et al., The Journal of Biological Chemistry, vol. 277, No. 51, pp. 49662-49667, Dec. 20, 2002.
Markus Wiksten et al., Journal of Neuroscience Research 71: pp. 338-352 (2003).
Markus Wiksten et al. Journal of Neuroscience Research 78: pp. 403-410 (2004).
Markus Wiksten et al. Journal of Neuroscience Research 78: pp. 411-419 2004.
Milman et al. (1980). Acta Derma Venerol. 60, 85-87.
Carney (2005). Drug. Discovery Today 10, 1268.
Nagaratnam et al. (2002). Journal of Clinical Neuroscience. 9, 473-476.
Hanafiah et al. (1989) Journal of the Royal Society of Medicine. 84, 48-49.
Miura et al. (2000). Experiemental Neurology. 166, 115-126.
Kawamata et al. (1997). PNAS. 94, 8179-8184.
Rogeji et al. (1989) JCB, 109, 823-.
Mercadante et al. (1998). Journal of Pain and Symptoms Management. 16, 317-322.
Hoyte et al. (2004). Current Molecular. Medicine. 4,131-136.
Sun et al. (1993) Neuroreport. 4, 1147-1150.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Biologically active peptides and their use for repairing... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Biologically active peptides and their use for repairing..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biologically active peptides and their use for repairing... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4179933

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.