Biologically active macrolides, compositions, and uses thereof

Details Biologically active macrolides, compositions, and uses thereof Biologically active macrolides, compositions, and uses thereof

2006-12-05

2006-12-05

Wilson, James O. (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C549S356000

Reexamination Certificate

active

07144918

ABSTRACT:
The present invention provides a compound of the formula (I).The present invention further provides a composition comprising at least one compound of the present invention and a pharmaceutically acceptable carrier, alone or in combination with at least one additional active agent. The present invention further provides a method of treating a condition treatable by the inhibition of vacuolar-type (H+)-ATPase and a method of treating cancer.

REFERENCES:
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Rashid et al.,J. Nat. Prod., 64(10), 1341-1344 (2001).
Rashid et al.,Tetrahedron Letters, 42, 1623-1626 (2001).

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