Biologically active lipids binding membrane receptors

Details Biologically active lipids binding membrane receptors Biologically active lipids binding membrane receptors

1990-03-13

1992-03-03

Lee, Lester L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260412, C11C 302

Patent

active

050930451

ABSTRACT:
Neutral lipids are provided characterized by binding to phorboid and ingenoid receptors. These lipids are found in a wide variety of cellular sources as well as milk and may be isolated by specific extraction and chromatographic procedures. Depending upon the source, the glycerides may be mono- or di-glycerides, wherein the total number of carbon atoms of the fatty acis is in the range of 18 to 26, so that the monoglyceride has a fatty acid of at least 18 carbon atoms, while the di-glyceride has a fatty acid of at least 14 carbon atoms. The long chain fatty acids have at least one site of olefinic unsaturation.

REFERENCES:
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patent: 3748348 (1973-07-01), Baratham
Shoyab et al., Journal of Biological Chemistry, vol. 256, No. 23, 12/10/81, pp. 12529-12534.
Markley, Klare, Fatty Acids--Their Chemistry, Properties Production and Uses, Part I, 1960, p. 334.
Welsh et al., Chemical Abstracts, vol. 96, 50892v, 1982.
Laher et al., Chemical Abstracts, vol. 99, 65605q, 1983.
Welsh et al., J. Food Safety (1981) 3(2):99-107.

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