Biologically active latex conjugate

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is organic

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436517, 436534, 436805, 523201, 524457, 524458, 524459, 524460, 524461, 525296, 525304, 525902, 5253261, 5253282, 525374, G01N 3354

Patent

active

045634319

ABSTRACT:
A biologically active latex conjugate prepared by the acidification of latex particles of a core/shell polymer having acetal groups in the shell, whereby said acetal groups are converted to aldehyde groups, and then bonding a biologically active substance having an amino group to said aldehyde groups by reductive amination.

REFERENCES:
patent: 4210723 (1980-07-01), Dorman et al.
patent: 4448908 (1984-05-01), Pauly et al.
Richard Juvet et al., J. Am. Chem. Soc., vol. 83, pp. 1560-1569, (1961), "Thermodynamics and Kinetics of the Alcoholysis of Acetals".

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