Biologically active compositions and methods of use

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...

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A61K 3700

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active

043270859

ABSTRACT:
The invention relates to water-soluble biologically active agents, having anti-infectious and adjuvant properties. They have the general formula ##STR1## wherein X, Y, Z, R.sub.2, R.sub.4 and R.sub.6 have the meanings defined in claim 1. The invention also relates to pharmaceutical compositions containing these compounds in association with a pharmaceutical vehicle, particularly an oil-free one.

REFERENCES:
patent: 4082735 (1978-04-01), Jones et al.
patent: 4082736 (1978-04-01), Jones et al.
patent: 4094971 (1978-06-01), Chedid et al.
patent: 4158052 (1979-06-01), Audibert et al.
patent: 4186194 (1980-01-01), Adam et al.
patent: 4220637 (1980-09-01), Audibert et al.
Audibert et al., Cellular Immunology, 21, 243-249, (1976).
Kotani et al., Biken Journal, 18, 105-111, (1975).
Adam et al., Biochem. and Biophys. Res. Commun., 72, (1976), pp. 339-346.
Borman et al., "Determinative Bacteriology", 1962, p. 347.

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