Biologically active complex

Details Biologically active complex Biologically active complex

2007-10-02

2007-10-02

Richter, Johann R (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Selenium or tellurium containing

Reexamination Certificate

active

10496729

ABSTRACT:
The invention relates to an aqueous solution containing at least one species selected from the group consisting of a 1:1 molar complex of TeO2with a moiety of formula (A) and ammonium salts thereof: HO—X—OH (A); where X is an optionally substituted divalent saturated hydrocarbon group containing 2-8 carbon atoms in the chain connecting the two OH groups; and its use for stimulating cells to produce cytokines and for treating mammalian diseases and conditions responsive to increased production of cytokines. The complex may be used also for treating mammalian cancer which is not responsive to increased production of cytokines.

REFERENCES:
patent: 4752614 (1988-06-01), Albeck et al.
patent: 4761490 (1988-08-01), Albeck et al.
patent: 4929739 (1990-05-01), Sredni et al.
patent: 5093135 (1992-03-01), Albeck et al.
patent: 0 194 393 (1986-09-01), None
patent: 333 263 (1989-09-01), None
Albeck, Ammon, et al., “Tellurium Compounds: Selective Inhibition of Cysteine Proteases and Model Reaction with Thiols”, Inorganic Chemistry, vol. 37, No. 8, pp. 1704-1712.
Denney, Donald, et al., “Preparation and NMR Studies of Tetraalkoxyselenuranes and Tetraalkoxytelluranes”, Journal of the American Cancer Society, 1981, vol. 103, pp. 2340-2347.
Giuseppe, Pietra, et al., “The Effects of Carcinogenic Chemicals in Newborn Mice”, Cancer, 1961, vol. 19, pp. 308-317.
Gills, Steven, et al., “T Cell Growth Factor: Parameters of Production and A Quantitative Microassay for Activity”, The Journal of Immunology, 1978, vol. 120, pp. 2027-2032.
Uchiyama, Takashi, et al., “A Monoclonal Antibody (anti-Tac) Reactive with Activated and Functionally Mature Human T Cells”, The Journal of Immunology, 1981, vol. 126, pp. 1398-1403.
Mbabazi, Jolocam, “Sugar complexes of Sn(IV), Sb(V), and Te (VI) hydroxyanions”, Carbohydrate Research, 1985, vol. 140, pp. 151-154.

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