Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Patent
1988-07-25
1993-04-06
Prescott, Arthur C.
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
560174, 560178, 560189, 560254, 549 71, 514512, 514547, 514548, 514533, C07C 6702
Patent
active
052005534
ABSTRACT:
Biologically active carboxylic acid esters which promote antitumor or immune response are selected from the group consisting of compounds having formulas (I), (II) and (III):
REFERENCES:
patent: 3293220 (1966-12-01), Minami et al.
patent: 3499028 (1970-03-01), McIver
patent: 3720706 (1973-03-01), Lapporte et al.
patent: 4012256 (1977-03-01), Kensler, Jr. et al.
patent: 4541944 (1985-09-01), Sanderson
Takeuchi et al., Chemical Abstracts, vol. 93:210255h 1980.
W. L. Badger, "Apparatus, Plant Equipment and Unit Operations", Chemical Abstracts, vol. 31, No. 18, Sep. 20, 1937, pp. 1036-1037.
Prasad et al., "Role of Cyclic AMP in Differentiation of Human Neuroblastoma Cells in Culture", Cancer 36, pp. 1338-1343 (1975).
Collins et al., "Terminal Differentiation of Human Promyelocytic Leukemia Cells Induced by Demithyl Sulfoxide and other Polar*".
Dexter et al., "Sodium Butyrate-Induced Alteration of Growth Properties and Glycogen Levels In Cultured Human Colon Carcinoma*".
Augeron et al., "Emergence of Permanently Differentiated Cell Line in Culture after Treatment with Sodium Butyrate", Can. Res. 44*.
McIntyre et al., "Effects of Sodium Butyrate and DMA on Human Pancreatic Tumor Cell Lines*", Euro. J. Can. Clin. Oncol., vol. 20*.
Heifetz et al., "The Effect of Butyrate on Sulfated Glycoprotein Biosythesis by Human Kidney Tumor Cells", J. Bio. Chem., vol. 256*.
Stevens et al., "Associated Effects of Sodium Butyrate on Histone Acetylation and Estrogen Receptor in the Human Breast Cancer*".
Reese et al., "Control of Growth, Morphology, and Alkaline Phosphatase Activity by Butyrate and Related Short-Chain Fatty*".
MacIntyre, E. H. et al., "The Responses in Culture of Human Tumour Astrocytes and neuroblasts to N.sup.6,O.sup.2' -Dibutyryl Adenosine*".
Macher et al., "Studies on the Mechanism of Butyrate-Induced Morphological Changes in KB Cells", Exp. Cell Res., 117, 95-102 (1978).
Prasad, "Butyric Acid: A Small Fatty Acid with Diverse Biological Functions", Life Sci., vol. 27, pp. 1351-1358 (1980).
Novogrodsky et al., "Effect of Polar Organic Compounds on Leukemic Cells", Cancer, vol. 51, pp. 9-14 (1983).
Rephaeli et al., "Effect of the Cell Differentiation Inducers Butyrate, Retinoic Acid and Low Dose Cytosine Arabinoside on*".
Januszewicz et al., "Butyric Acid: Inhibition of Non-Leukemic and Chronic Myeloid Leukemia Granulocyte Macrophage Clonal Growth*".
Wheeler et al., "Orally Active Esters of Cephalosporin Antibiotics", J. Med. Chem., vol. 22, No. 6, pp. 657-661 (1979).
Daehne et al., "Acyloxymethyl Esters of Ampicillin", J. Med. Chem., vol. 13, No. 4, pp. 607-6122 (1970).
Bodin et al., "Bacampicillin: a New Orally Well-Absorbed Derivative of Ampicillin", Antimicrob. Ag. Chemother., vol. 8, pp. 518-525 (1975).
Foresta et al., "A New Cephalosporin Derivative (ST-21) Orally Administered in Laboratory Animals", Arzneim-Forsch./Drug. Res.*
Clayton et al., "BRL.8988 (Talamplicillin), a Well-Absorbed Oral Form of Ampilicillin", Antimicrobial Ag. Chemotherapy, vol. 5.
Roholt, Antimicrob. Chemother. 3 (suppl. B):710 (1977).
"Developmental Therapeutics Program, Division of Cancer Treatment National Cancer Institute", NIH Publication 84-2635.
Miller et al., "Clinical Pharmacology of Sodium Butyrate in Patients with Acute Leukemia", Eur. J. Clin. Oncol., vol. 23*.
Fujimoto, Koichi et al., "Studies on Orally Active Cephalosporin Esters", J. Antibiotics, vol. XL, No. 3, pp. 370-384 (1987).
Man et al., "Boron Fluoride Catalyzed Addition of Aliphatic Anhydrides to Aldehydes", J. Am. Chem. Soc., vol. 72, pp. 847-848 (1950).
Nudelman Abraham
Rephaeli Ada
Shaklai Matitiahu
Garner Vivian
Kupat Holim Health Insurance Institution of the General Federati
Prescott Arthur C.
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