Biologically active acrylonitrile-based copolymeric membrane

Details Biologically active acrylonitrile-based copolymeric membrane Biologically active acrylonitrile-based copolymeric membrane

1984-06-08

1987-11-10

Naff, David M.

Chemistry: molecular biology and microbiology

Carrier-bound or immobilized enzyme or microbial cell;...

Enzyme or microbial cell is immobilized on or in an organic...

435174, 435181, 436531, 436532, 530815, 530816, C12N 1108, C12N 1106, C12N 1100, G01N 33545

Patent

active

047057530

ABSTRACT:
A membrane is produced by dissolving, in a water-miscible solvent, a water insoluble copolymer of acrylontrile with at least one monomer selected from the group consisting of an aminostyrene, a vinyl pyridine and an N-hydroxy-containing-substituent-acrylamide, casting said solution to form a thin layer of solution, contacting said solution with water thereby to coagulate the copolymer into a film, and washing away from the copolymer film the solution of solvent and water. The amine or hydroxy group of the copolymer is then activated and coupled with a ligand such as glucose isomerase, chymotrypsin or Protein A. The coupled membranes can then be used for biological separations and reactions.

REFERENCES:
patent: 3808305 (1974-04-01), Gregor
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patent: 3939041 (1976-02-01), Lartigue et al.
patent: 3964973 (1976-06-01), Hradil et al.
patent: 4033817 (1977-07-01), Gregor
patent: 4352884 (1982-10-01), Nakashima et al.
patent: 4371612 (1983-02-01), Matsumoto et al.
Miekka et al., "Chem. Abstracts", vol. 97, (1982), Abstract #133409q.

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