Biologically active 4H-benzo [1,4] oxazin-3-ones

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

Reexamination Certificate

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C514S230500, C544S105000

Reexamination Certificate

active

06908908

ABSTRACT:
The invention is directed to 4h-benzo[1,4]oxazin-3-ones useful as peroxisome proliferator activated receptor gamma (PPARγ) agonists or antagonists. Pharmaceutical compositions comprising compounds of the present invention and methods of treating conditions such as NIDDM and obesity are also disclosed.

REFERENCES:
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patent: WO 91 19702 (1991-12-01), None
patent: WO 96 04260 (1996-02-01), None
patent: WO 97 17333 (1997-05-01), None
patent: WO 97 28167 (1997-08-01), None
patent: WO 99 20614 (1999-04-01), None
patent: PCT/US 01/15383 (2001-05-01), None
Hilliard, Jamese J. et. al., “Multiple mechanisms of action for inhibitors of histidine protein kinases from bacterial two-component systems” Antimicrob. Agents Chemother. (1998), 43(7), 1693-1699, XP002171516 the whole document, especially p. 1695, FIG. 1.

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