Biological stain composition, method of preparation and method o

Details Biological stain composition, method of preparation and method o Biological stain composition, method of preparation and method o

1993-06-07

1994-12-13

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

5142262, 544 37, A61K 3154

Patent

active

053728017

ABSTRACT:
A biological stain composition contains toluidine blue O and a pharmaceutically acceptable oxidizing agent to convert any leuco toluidine blue O to the chromo form. A dry composition for preparing the stain includes the toluidine blue O, the oxidizing agent and an effervescent agent. These compositions are preferably buffered to improve shelf stability and clinical consistency. Compositions for intra-oral application contain a flavoring agent.

REFERENCES:
patent: 3743088 (1973-07-01), Henkin
patent: 4181128 (1980-01-01), Swartz
patent: 4321251 (1982-03-01), Mashberg
patent: 4977177 (1990-12-01), Bommer et al.
patent: 5018531 (1991-05-01), Hartman
patent: 5069754 (1991-12-01), Watanabe et al.
Remington Pharmaceutical Sciences (1975) Ed: Hoover, John E., pp. 1368, 1369, & 1413-1418.

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