Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1989-05-10
1991-11-12
Warden, Robert J.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
422 681, 422 8209, 356318, 356445, 436805, 435808, G01N 2100
Patent
active
050646192
ABSTRACT:
A surface plasmon resonance (SPR) detector includes a laser source for generating radiation which is reflected off a concave reflector to a point or line of incidence on the interface between a glass slide and a metal layer. A single pencil beam from the laser is scanned by a moving mirror across a small arc, covering those angles of incidence within which surface plasmon resonance occurs. A sensitive, for example antibody, layer overlies the metal layer to form a combined layer, and a sample to be tested is passed across the antibody layer. Any binding which occurs with the antibody layer results in the refractive index of the layer changing, and this change may be detected by monitoring the strength of the beam internally reflected at the point or line. A light detector enables the beam to be measured.
REFERENCES:
patent: 3645631 (1972-02-01), Gupta
patent: 4297032 (1981-10-01), Temple
patent: 4844613 (1989-07-01), Batchelder et al.
patent: 4857273 (1989-08-01), Stewart
patent: 4880752 (1989-11-01), Keck et al.
patent: 4889427 (1989-12-01), Van Veen et al.
Patent Abstracts of Japan, vol. 12, No. 88, Mar. 23, 1988, p. 4 P 678, "Photochemical Analyzer".
"Instantaneous Observation of Angular Scan-Attenuated Total Reflection Spectra", K. Oda and M. Fukui, Optics Communications, vol. 59, No. 5/6, Oct. 1, 1986, pp. 361-365.
"A One-Dimensional Focusing Critical Angle Refractometer for Mass Transfer Studies", K. W. Beach et al., Review of Scientific Instruments, vol. 43, No. 6, Jun. 1972, pp. 925-928.
"Surface Plasmon Resonance for Gas Detection and Biosensing", Liedberg, Nylander and Lundstrom, Sensors and Actuators, vol. 4, 1983, pp. 299-304.
Amersham International plc
Trembley Theresa A.
Warden Robert J.
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