Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1992-08-17
1994-02-08
Knode, Marian
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435126, 435148, 435189, C12P 1706, C12P 1704, C12P 726, C12N 902
Patent
active
052847594
ABSTRACT:
Meta-hydroxyphenylacetylenes are produced from phenyl-substituted ketal or acetal precursors. Using biotransformation processes, these precursors serve as substrates that are converted to cis-dihydrodiol intermediates. The cis-dihydrodiols can be converted chemically to the corresponding meta-substituted compounds, e.g., meta-substituted phenols, and then to m-hydroxyphenylacetylene, which is an intermediate needed to produce acetylene-terminated resins. The biotransformation step employs arene-2,3-dioxygenase in intra- or extra- cellular form.
REFERENCES:
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Mader Roger A.
Tautvydas Kestutis J.
Busse Paul W.
Griswold Gary L.
Kirn Walter N.
Knode Marian
Minnesota Mining and Manufacturing Company
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