Biological process for the preparation of rifamycin derivatives

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435190, 435911, C12P 1718, C12N 904, C12R 1645

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active

044317352

ABSTRACT:
A biological process for converting rifamycin B to rifamycin O, rifamycin S or rifamycin SV by treatment with the whole cell, the cell extract, or the immobilized enzyme of Humicola spp. (ATCC 20620) or Monocillium spp. (ATCC 20621) is provided. The process also includes the recovery of rifamycin B in the fermentation broth after conversion to rifamycin O, rifamycin S or rifamycin SV.

REFERENCES:
patent: 3871965 (1975-03-01), White et al.
patent: 3871966 (1975-03-01), Pasqualucci et al.

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