Biological process for producing steroids hydroxylated at the 25

Details Biological process for producing steroids hydroxylated at the 25 Biological process for producing steroids hydroxylated at the 25

1998-12-23

2000-03-28

Dees, Jose' G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing a...

C12P 3306

Patent

active

060430508

ABSTRACT:
A biological process for producing steroids hydroxylated at the 25-position thereof comprises adding steroids (excluding cholesterol) to the cells or culture liquid of a microorganism of the genus Amycolata or Sphingomonas capable of hydroxylating the steroids at the 25-position thereof to convert a hydrogen atom bonded to a carbon atom at the 25-position of each steroid into hydroxyl group. By this process, steroids(other than cholesterol) can be biologically hydroxylated at the 25-position by using microorganisms other than those of the genus Streptomyces.

REFERENCES:
Abstract of Japanese Patent 7123997 A, 1995.

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