Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...
Patent
1992-02-25
1993-06-01
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing a...
435 60, 435946, C12P 3320, C12P 3310, C12R 189
Patent
active
052158942
ABSTRACT:
The present invention is concerned with a novel biotransformation process for producing 17.beta.-N-monosubstituted carbamoyl-11-oxo-4-aza-5-.alpha.-androst-3-ones of the formula: ##STR1## These compounds are testosterone 5-.alpha. reductase inhibitors and are produced via a claimed novel biotransformation process using the green algae, Selenastrum capricornutum.
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Arison Byron H.
Carlin Josephine R.
Venkataramani Edamanal S.
Browder Monte R.
Caruso Charles M.
Lilling Herbert J.
Merck & Co. , Inc.
North Robert J.
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