Biological process for preparing optically active lactic acid

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound

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435280, 435822, C12B 742, C12B 4100, C12B 756, C07C 5908

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active

052348261

ABSTRACT:
A process for preparing an optically active lactic acid comprising subjecting DL-lactonitrile or acetaldehyde and prussic acid to the action of a microorganism belonging to the genus Enterobacter, Arthrobacter, Caseobacter, Brevibacterium, Aureobacterium, Escherichia, Micrococcus, Streptomyces, Flavobacterium, Aeromonas, Nocardia, Mycoplana, Cellulomonas, Erwinia, Candida, Pseudomonas, Rhodococcus, Bacillus, Alcaligenes, Corynebacterium, Microbacterium or Obsumbacterium, or treated microbial cells thereof, which the microorganism is capable of stereospecifically hydrolyzing a nitrile in a polar solvent. D-Lactic acid or L-lactic acid can be produced directly in a predominant proportion from the starting materials.

REFERENCES:
patent: 3940316 (1976-02-01), Commeyras
Derwent Abs. 84-054368/09 Markoy (et al) SU1011630.
Derwent Abs 92-02964/04 Asahi Chem J03277292 (Dec. 1991).
Derwent Abs 86-184583/29 Enomoto et al. GP-187680 (Jul. 1986).

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