Biological pacemakers including mutated...

Details Biological pacemakers including mutated... Biological pacemakers including mutated...

2006-11-30

2011-12-13

Li, Q. Janice (Department: 1633)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S093200, C424S093210, C536S023100, C435S320100

Reexamination Certificate

active

08076305

ABSTRACT:
A composition for implantation into cardiac tissue includes a biological pacemaker that, when implanted, expresses an effective amount of a mutated hyperpolarization-activated and cyclic nucleotide-gated (HCN) isoform to modify Ihwhen compared with wild-type HCN. Methods for implementing each of the biologocal pacemakers include implanting each of biologocal pacemakers into cardiac tissue.

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