Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving viable micro-organism
Reexamination Certificate
2000-04-20
2010-12-14
Kim, Taeyoon (Department: 1651)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving viable micro-organism
C422S026000, C422S119000
Reexamination Certificate
active
07851178
ABSTRACT:
The present invention relates to a method of evaluating the efficiency of sterilization processes by measurement of degradation level of prion protein indicators. When exposed to sterilization conditions, prion indicators are degraded in a manner to proportionally indicate the level of degradation of prion proteins themselves on medical devices or other surfaces usable in surgery and health cares.
REFERENCES:
patent: 5357636 (1994-10-01), Dresdner et al.
patent: 5633349 (1997-05-01), Reichl
Safar et al. Thermal stability and conformational transitions of scrapie amyloid (prion) protein correlate with infectivity. 1993, Protein Science 2:2206-2216.
Feldman et al. Compatibility of Medical Devices and Materials with Low-Temperature Hydrogen Peroxide Gas Plasma. 1997. http://www.epotek.com/SSCDocs/whitepapers/Tech%20Paper%2059.pdf.
Prusiner. Prions. 1998. PNAS 95:13363-13383.
Parkin et al. Amyloid precursor protein, although partially detergent-insoluble in mouse cerebral cortex, behaves as an atypical lipid raft protein. Biochem. J. 1999 344:23-30.
DeArmond. Alzheimer's disease and Creutzfeldt-Jakob disease: overlap of pathogenic mechanisms. Curr. Opin. Neurol. 1993, Abstract.
Wickner. 1994. [URE3] as an Altered URE2 Protein: Evidence for a prion analog inSaccharomyces cerevisiae. Science. 264:566-569.
Coustou et al. 1997. The protein product of the het-s-heterokaryon incompatibility gene of the fungusPodospora anserinabehaves as a prion analog. PNAS 94:9773-9778.
Taylor et al. 1999. Prion Domain Initiation of Amyloid Formation in Vitro from Native Ure2p. Science. 283:1339-1343.
Glover. J.R., Kowal, A.S., et al. Cell (1997) 89:811-819.
Hill, A.F., Antoniou, M. and Collinge, J., Journal of General Virology (1999) 80:11-14.
Jarvis, W.R. Hospital Infection Control (1985) 12 (12):145-148.
King, C., Tittmann, P. et al. Proc. Natl. Acad. Sci. USA (1997) 94:6618-6622).
Rosenberg, R.N. et al., Annals of Neurology (1986) 19(1):75-77.
Sambrook, J., Fritsch, E.F.; and Maniatis, T. Molecular Cloning, a laboratory manual. Cold Spring Harbor Laboratory Press, 2nd edition, 1989.
Tuite MF and Lindquist SL , TIG (1996) 12 (11): 467-471.
Wickner, RB. PNAS (1997) 94 : 10012 to 10014.
Dental Products Report, Oct. 1995, pp. 96-104.
Belhumeur Pierre
Julien Karine
Marchand Richard
Tabrizian Maryam
Yahia L'Hocine
Kim Taeyoon
Klauber & Jackson LLC
Polyvalor s.e.c.
Valorisation-Recherche
LandOfFree
Biological indicators for validating a prion... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Biological indicators for validating a prion..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Biological indicators for validating a prion... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4157159