Biological imaging emulsions containing alkyl- or alkylglyceroph

Details Biological imaging emulsions containing alkyl- or alkylglyceroph Biological imaging emulsions containing alkyl- or alkylglyceroph

1993-11-24

1995-08-08

Geist, Gary L.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

424 94, 424 95, 514938, 1256534, A61B 5055, A61B 808, A61K 4904, A61K 31685

Patent

active

054396697

ABSTRACT:
Oil and water emulsions containing alkylphosphoryl choline or alkylglycerophosphoryl choline surfactants are disclosed. The surfactants have the following general structures: ##STR1## In the above general structures, R.sub.1, R.sub.2 or R.sub.3 is alkyl, alkenyl, fluoroalkyl and alkenyl; and PC is the phosphoryl choline. The emulsions are useful as oxygen transport agents, artificial bloods or red blood cell substitutes.
The emulsions are also useful as contrast agents for biological imaging by the modalities of nuclear magnetic resonance, x-ray and ultra sound.

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