Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Bacteria or actinomycetales
Patent
1997-10-06
2000-07-04
Marx, Irene
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Bacteria or actinomycetales
43525233, 4352521, 4351723, A01N 6300
Patent
active
060835001
ABSTRACT:
The invention includes novel strains of E. coli and methods for treating livestock with strains of the invention to inhibit growth of S. typhimurium as well as other pathogenic enterobacteria, such as E. coli 0157:H7, in the intestinal tract of treated animals. By inhibiting growth of such contaminant pathogenic organisms in the intestinal tract of treated animals, the number of such organisms living in the animals, or excreted into the environment, is reduced or eliminated. The potential for re-introduction and for contamination of meat and other products is concomitantly reduced or eliminated.
REFERENCES:
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Kolter, R. et al. (1992) "Genetics of Ribosomally Synthesized Peptide Antibiotics," Ann. Rev. Microbiol. 46:141-163.
Moreno, F. et al. (1995) Biotechnology, Series 28 Genetics and Biochemistry of Antibiotics Production, Ch. 11, "Microcins," Pp. 307-321.
O'Brien, G.J. (1994) "Colicin 24, a new plasmid-borne colicin from a uropathogenic strain of Escherichia coli"Plasmid 31:288-296.
Pugsley, A.P. (1984) "The ins and outs of colicins. Part I: Production, and translocation across membranes," Microbiol. Sci. 1:168-175.
Shotts, Jr. Emmett B.
Wooley Richard E.
Marx Irene
University of Georgia Research Foundation Inc.
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