Biological contraceptive for males

Details Biological contraceptive for males Biological contraceptive for males

1985-10-01

1988-07-26

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

C-o-group doai

514841, A61K 31045

Patent

active

047600977

ABSTRACT:
A male contraceptive preparation is disclosed. The contraceptive preparation consists essentially of 1,2,3-trihydroxypropane in solution in a suitable carrier such as distilled water or saline solution. The method of contraception comprises injecting the contraceptive preparation into the testes. The 1,2,3-trihydroxypropane has been found to act as a potent inhibitor of spermatogenesis, resulting in long term infertility, with no apparent effect on libido, secondary sex characters, mating behaviour and hormone levels. There are no observed side effects and no observed effects on other aspects of reproductive and hormonal biology.

REFERENCES:
patent: 4356189 (1982-10-01), Stagg et al.
Lachmar et al-"The Theory & Practice of Industrial Pharmacy" (Textbook), 2nd Ed., 1976, pp. 586-589.

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